第42回

日本基礎老化学会大会

7 June (Fri)

Exhibition building, Room 15 (Meeting Room 4)

9:00 Opening Remarks President: Akihito Ishigami

9:10~10:10

Oral Presentation 1  O1

Chairpersons

Yuri Miura
Koju Fukui

O1-1/P-01
9:10

Decline of NO synthesis causes volume expansion and salt-sensitive hypertension
Shimosawa T

O1-2/P-02
9:21

Revising the class of lipoproteins
Konishi T

O1-3/P-03
9:32

Blood pressure-independent increase in the cortical blood flow induced by manual acupuncture of the auricular region in rats
Uchida S

O1-4/P-04
9:43

Generation of mouse indicating and eliminating senescent cells for elucidating the mechanism of immunosenescence
Kamei Y

O1-5/P-05/
/JGS-P
9:54

Molecular mechanism of age-dependent synaptic dysfunctions in
Alzheimer’s disease
Tsuda L

 

 

10:10~11:40

Symposium Session S1 “Functional foods as regulators of aging”

Chairpersons

Shuichi Yanai
Masumi Iketani

Debater

Keiichi Higuchi

10:10

Opening Address

S1-1  10:15

Tocotrienols improve hydrogen peroxide-induced neurite degeneration
Fukui K

S1-2  10:27

Impact of water soluble soy isoflavones on the gut microbiome and aging
Maruyama M

S1-3  10:39

Coenzyme Q administration improves age-related decline of motor cortex activities
Inoue R

S1-4  10:51

Suppression of brain aging by green tea
Unno K

S1-5  11:03

Foods with Function Claims for locomotive syndrome
Otsuka Y

11:15

Discussion

 

 

12:00~13:00

Luncheon Seminar RISOU Corp.

L1

Vitamin C application to the skin is more effective before exposure to ultraviolet light (UVB)
Akihito Ishigami

 

 

13:10~14:30

Symposium Session S2 “Nuclear architecture and aging”

Chairpersons

Takahiko Shimizu
Michihiko Fujii

S2-1  13:10

Physical forces, Nucleus, Transcription and Aging, plus Exercise pill
Ogura T

S2-2  13:30

Involvement of nuclear actin in genome functions and cell senescence
Harata M

S2-3  13:50

The role of lamin B receptor in cellular senescence
En A

S2-4  14:10

Mitochondrial stress response regulates bone remodeling via epigenome-nuclear lamina axis in osteocytes
Shimizu T

 

 

14:40~16:00

Symposium Session S3 “Senescence signal and cancer”

Chairpersons

Masataka Sugimoto
 Shohei Shinozaki

S3-1  14:40

Multi-faceted Functions of Tumor Suppressor p53
Tanaka T

S3-2  15:00

Cellular senescence and SASP: the mechanism of induction and the role in vivo
Ohtani N

S3-3  15:20

Rapamycin slows aging and changes cancer incidence
Ito T

S3-4  15:40

Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle
Shinozaki S

 

 

16:10~17:30

Symposium Session S4 “Stem cell aging, frailty and progeria syndrome”

Chairpersons

Takamasa Ishii
Yusuke Ono

S3-1  14:40

Epigenetic alterations in aged hematopoietic stem cells and age-associated malignancies
Iwama A

S3-2  15:00

Positional memory of muscle stem cells
Ono Y

S3-3  15:20

Elucidation of Mechanism Underlying Premature Aging in Werner syndrome with the Disease-Specific Induced Pluripotent Stem Cells
Shimamoto A

S3-4  15:40

Pathophysiological changes in Primrose or 3q13.31 deletion syndromes
Ishii T

 

 

8 June (Sat)

Exhbition building, Room 15 (Meeting Room 4)

9:00~10:20

Symposium Session S5 “Oriental medicine for promoting health and longevity”

Chairpersons

Sae Uchida
Nobuhiro Watanabe

S5-1  9:00

The effect of gentle mechanical skin stimulation on urinary bladder function
Watanabe N

S5-2  9:15

Protective effects of Ginsenoside Rb1 on cardiovascular system
Son BK

S5-3  9:30

Neuroprotective and Neurogenic Effects of Dietary Phytochemicals
Lee J

S5-4  9:45

Anti-obesity mechanisms of Kampo medicine
Akaki J

S5-5  10:00

Effects of evodiamine for healthy aging
Yamashita H

10:15

Discussion

 

 

10:20~11:40

Symposium Session S6 “Animal models in aging research”

Chairpersons

Hiroshi Manya
Yasunori Fujita

S6-1  10:20

Genes regulating lifespan in Drosophila melanogaster
Aigaki T

S6-2  10:36

Investigation of the healthy long life signals using rodents: focusing on the target molecules of calorie restriction
Chiba T

S6-3  10:52

Protein citrullination: a potential biomarker and therapeutic target in aging and neurodegeneration
Choi EK

S6-4  11:08

Role of Mitochondrial Respiratory Supercomplex Assembly Factor in Health and Disease
Inoue S

S6-5  11:24

The long-lived and cancer-resistant rodent, the naked mole-rat
Miura K

 

 

12:00~13:00

Luncheon Seminar Merodian Co. ltd.

L2

Recent advances in molecular hydrogen medicine
Ikurou Ohsawa

 

 

13:00~14:30

Poster Sessions

Exhibition building, Exhibition Hall 1+2

Presentation time:

odd number 13:00~13:45
even number 13:45~14:30

P-01/O1-1

Decline of NO synthesis causes volume expansion and salt-sensitive hypertension
Shimosawa T

P-02/O1-2

Revising the class of lipoproteins
Konishi T

P-03/O1-3

Blood pressure-independent increase in the cortical blood flow induced by manual acupuncture of the auricular region in rats
Uchida S

P-04/O1-4

Generation of mouse indicating and eliminating senescent cells for elucidating the mechanism of immunosenescence
Kamei Y

P-05/O1-5
/JGS-P3-1

Molecular mechanism of age-dependent synaptic dysfunctions in Alzheimer’s disease
Tsuda L

P-06/Y-01
/JGS-P3-2

The Ubiquitin-Proteasome System Is Indispensable for the Maintenance of Muscle Stem Cells
Kitajima Y

P-07/Y-02

Protective effect of vitamin C on vancomycin-induced nephrotoxicity
Takigawa M

P-08/Y-03

FoxO3a is an anti-aging factor for age-related skin atrophy and pigmentation
Kim J

P-09/Y-04

Estrogen deficiency accelerates senescence-associated T cells accumulation by CXCL13 production in salivary gland epithelial cells
Shikama Y

P-10/Y-05

Vitamin C deficiency causes skeletal muscle atrophy and a deterioration in physical performance
Yatsu T

P-11/Y-06

Analysis of the intracellular and membrane glycan profiles with cellular senescence and human aging
Itakura Y

P-12/Y-07

Proteomic analysis of extracellular vesicles derived from serum of Alzheimer’s disease patients
Kawakami K

P-13/Y-08

Analysis of the molecular mechanism underlying chronic inflammation in skin aging
Kawaguchi K

P-14/Y-09

Age-associated changes in DNA methylation in skeletal muscle of mice
Kawanishi N

P-15/Y-10

Anti-obesity effect of Kampo medicine "Daisaikoto" in ovariectomized mice as a model of menopausal obesity
Hashimoto S

P-16/Y-11

Mechanical stimulation to the pharynx promotes secretion of thyroxine and calcitonin, metabolism regulating hormones, via the superior laryngeal nerve
Iimura K

P-17/Y-12

Drinking hydrogen-rich water prevents endothelial cell senescence of the aorta via inhibition of inflammation in atherogenesis
Iketani M

P-18

The mechanism of lipid droplet-associated protein perilipin1 reduction in obese WAT
Mizunoe Y

P-19

Chronic stress causes excessive aggression by altering synaptic actin dynamics in the mPFC
Tada H

P-20

Involvement of DOCK11 in B-cell immune responses
Sakamoto A

P-21

Identification of CD11b-expressing small extracellular vesicles in mice with sepsis
Fujita Y

P-22

Molecular mechanism that controls expression of mitochondrial function-associated
Uchiumi F

P-23

Regulation of fat utilization and adiposity by NPY deficiency in female mice
Park S

P-24

Analysis of odontoblast-like differentiation of TNF-α-stimulated human senescent dental pulp cells
Nozu A

P-25

Regulation of glycan structure in SMG mucin by the polycomb group protein Bmi1
Yamakoshi K

P-26

Senescence alters the peripheral circadian rhythm in endothelial cell
Maeda M

P-27
/JGS-P3-3

Reduction of α-Klotho and pulmonary emphysema in aging
Manya H

P-28

Homeostatic mechanisms of miR-142 in tissue-specific miR-142 knockout mice
Mori R

P-29

Age-related nephrosclerosis is partially improved in aP2-CREG1-Tg
Hashimoto M

P-30

Analysis of the phenotype of ubiquitous and brain specific WDR6 knock out mice
Komatsu T

P-31

An essential trace element zinc is involved in skin dryness and skin barrier function
Nishida K

P-32

Proteomic analysis of formalin-fixed paraffin-embedded kidney tissues from patients with diabetic nephropathy
Tsumoto H

P-33

Effect of the constituent of Kampo medicine “Boufutsushosan” on visceral fat accumulation
Tanaka T

P-34

Dibutyl phthalate causes cell cycle arrest of neural progenitor cell and impairs hippocampal neurogenesis
Yang S

P-35

Usnic acid protects dopaminergic neurons in the MPTP-induced Parkinson’s disease model through suppressing neuroinflammation
Lee S

P-36

FoxO6-mediated IL-1β induces hepatic insulin resistance and senoinflammation via the TF/PAR2 pathway
Kim DH

P-37

Neuroprotective effect of MHY908, a novel PPAR α/γ dual agonist, on the MPTP-induced Parkinson’s disease model
Lee Y

P-38/S-01/O2-1

The effect of obesity-responsive E3 ubiquitin ligase Wwp1 on adipocytes
Hoshino S

P-39/S-02/O2-2

Functional analysis of calorie restriction-inducible mitochondrial signal peptidase MIPEP and search for its promoter
Hirao Y

P-40/S-03/O2-3

Mechanism of mitochondrial biogenesis reduction in white adipose tissue of obese mice
Arikawa T

P-41/S-04/O2-4

Development of biomarker for the early diagnosis of Alzheimer’s disease in mild cognitive impairment stage
Mori Y

P-42/S-05/O2-5

Identification of age-related genes using single cell analysis
Doshida Y

P-43/S-06/O2-6

Identification of mouse adipose-derived stem cells by comprehensive single-cell transcriptome
Sano H

P-44/S-07

Drinking H2-water prevents atherogenesis and affects the splenic telomere in Apoe-/- mice
Masaki K

P-45/S-08

DNA polymerase theta (POLQ) is important for repair of replication fork collapse resulting DNA double-strand breaks
Wang Z

P-46/S-09

Analysis of the mechanisms for the induction of cellular senescence by 5-bromodeoxyuridine
Watanabe K

P-47/S-10

Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues
Hisamatsu D

 

 

14:30~15:30

Oral Presentation 1  O1

Chairpersons

Yuri Miura
Kouji Fukui

O2-1/P-38/S-01
14:30

The effect of obesity-responsive E3 ubiquitin ligase Wwp1 on adipocytes
Hoshino S

O2-2/P-39/S-02
14:40

Functional analysis of calorie restriction-inducible mitochondrial signal peptidase MIPEP and search for its promoter
Hirao Y

O2-3/P-40/S-03
14:50

Mechanism of mitochondrial biogenesis reduction in white adipose tissue of obese mice
Arikawa T

O2-4/P-41/S-04
15:00

Development of biomarker for the early diagnosis of Alzheimer’s disease in mild cognitive impairment stage
Mori Y

O2-5/P-42/S-05
15:10

Identification of age-related genes using single cell analysis 
Doshida Y

O2-6/P-43/S-06
15:20

Identification of mouse adipose-derived stem cells by comprehensive single-cell transcriptome
Sano H

 

 

 

 

大会事務局

東京都健康長寿医療センター研究所  老化制御研究チーム 分子老化制御 
173-0015 東京都板橋区栄町35-2
TEL.03-3964-3241(内4304)
メールアドレス:jsbmg2019@aging-regulation.jp