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2010 2009 2008年以前

研究実績 2010年

原著論文 総説および解説 著書

原著論文

  1. Amano, A., Aigaki, T., Maruyama, N., Ishigami, A.: Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice. Arch Biochem Biophys 496: 38-44 (2010)
  2. Hasegawa, G., Yamasaki, M., Kadono, M., Tanaka, M., Asano, M., Senmaru, T., Kondo, Y., Fukui, M., Obayashi, H., Maruyama, N., Nakamura, N., Ishigami, A.: Senescence marker protein-30/gluconolactonase deletion worsens glucose tolerance through impairment of acute insulin secretion. Endocrinology 151: 529-536 (2010)
  3. Ishigami, A., Maruyama, N.: Importance of research on peptidylarginine deiminase and citrullinated proteins in age-related disease. Geriatrics & Gerontology International 10: S53-S58 (2010)
  4. Jang, B., Jin, J.K., Jeon, Y.C., Cho, H.J., Ishigami, A., Choi, K.C., Carp, R.I., Maruyama, N., Kim, Y.S., Choi, E.K.: Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease. Acta Neuropathol 119: 199-210 (2010)
  5. Koike, K., Kondo, Y., Sekiya, M., Sato, Y., Tobino, K., Iwakami, S.I., Goto, S., Takahashi, K., Maruyama, N., Seyama, K., Ishigami, A.: Complete lack of vitamin C intake generates pulmonary emphysema in senescence marker protein-30 knockout mice. Am J Physiol Lung Cell Mol Physiol 298: L784-792 (2010)
  6. Maruyama, N., Ishigami, A., Kondo, Y.: Pathophysiological significance of senescence marker protein-30. Geriatrics & Gerontology International 10: S88-S98 (2010)
  7. Ogiwara, Y., Mori, S., Iwama, M., Sawabe, M., Takemoto, M., Kanazawa, N., Furuta, K., Fukuda, I., Kondo, Y., Kimbara, Y., Tamura, Y., Chiba, Y., Araki, A., Yokote, K., Maruyama, N., Ito, H.: Hypoglycemia due to ectopic secretion of insulin-like growth factor-I in a patient with an isolated sarcoidosis of the spleen. Endocr J 57: 325-330 (2010)
  8. Park, H., Ishigami, A., Shima, T., Mizuno, M., Maruyama, N., Yamaguchi, K., Mitsuyoshi, H., Minami, M., Yasui, K., Itoh, Y., Yoshikawa, T., Fukui, M., Hasegawa, G., Nakamura, N., Ohta, M., Obayashi, H., Okanoue, T.: Hepatic senescence marker protein-30 is involved in the progression of nonalcoholic fatty liver disease. J Gastroenterol 45: 426-434 (2010)
  9. Park, J.K., Hong, I.H., Ki, M.R., Chung, H.Y., Ishigami, A., Ji, A.R., Goo, M.J., Kim, D.H., Kwak, J.H., Min, C.W., Lee, S.S., Jeong, K.S.: Vitamin C deficiency increases the binucleation of hepatocytes in SMP30 knock-out mice. J Gastroenterol Hepatol 25: 1769-1776 (2010)
  10. Park, J.K., Ki, M.R., Lee, H.R., Hong, I.H., Ji, A.R., Ishigami, A., Park, S.I., Kim, J.M., Chung, H.Y., Yoo, S.E., Jeong, K.S.: Vitamin C deficiency attenuates liver fibrosis by way of up-regulated peroxisome proliferator-activated receptor-gamma expression in senescence marker protein 30 knockout mice. Hepatology 51: 1766-1777 (2010)
  11. Sato, Y., Uchiki, T., Iwama, M., Kishimoto, Y., Takahashi, R., Ishigami, A.: Determination of dehydroascorbic acid in mouse tissues and plasma by using tris(2-carboxyethyl)phosphine hydrochloride as reductant in metaphosphoric acid/ethylenediaminetetraacetic acid solution. Biol Pharm Bull 33: 364-369 (2010)
  12. Shimada, N., Handa, S., Uchida, Y., Fukuda, M., Maruyama, N., Asaga, H., Choi, E.K., Lee, J., Ishigami, A.: Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain. J Neurosci Res 88: 798-806 (2010)

総説および解説

  1. 岸本祐樹, 石神昭人: ビタミンC輸送体SVCT1の遺伝子欠損は腎臓でのビタミンC再吸収を低下させる. ビタミン 84: 490-492 (2010)
  2. 石神昭人: ビタミンCと抗老化. 理大科学フォーラム 27: 26-30 (2010)
  3. 石神昭人: 最新ビタミン学講話-1- ビタミンC. Functional Food 4: 172-176 (2010)
  4. 石神昭人: 加齢指標タンパク質SMP30/GNLノックアウトマウスを用いた抗老化研究. YAKUGAKU ZASSHI 130: 25-28 (2010)
  5. 石神昭人, 萬谷博: 老化モデル動物を用いた抗老化研究へのアプローチ. YAKUGAKU ZASSHI 130: 1-2 (2010)
  6. 天野晶子, 石神昭人: ビタミンCによるウェルナー症候群の症状改善効果. ビタミン 84: 434-436 (2010)

著書

  1. 石神昭人: ビタミンC. ビタミン総合事典: 405-412 (2010)
  2. 石神昭人, 後藤佐多良: タンパク質の細胞内導入法;第3章オルガネラ異常の研究法. 生物薬科学実験講座 第5巻 ―細胞の構造とオルガネラ: 189-195 (2010)
  3. 石神昭人, 後藤佐多良: タンパク質の加齢変化. 新老年学: 29-42 (2010)

 

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